Skip to content

In an emergency call 999 · Urgent NHS advice 111

Substance Use InformationSupport without stigma · UK

Harm reduction

Reducing risk, whatever stage you're at

Harm reduction means taking practical steps to stay safer and healthier. You do not have to stop using, or plan to stop, to deserve accurate information and good care.

Core principles

Six principles that reduce risk

These apply across substances and are drawn from established UK harm-reduction practice.

  • Never use alone where you can avoid it

    If someone is with you, they can call 999 and respond if something goes wrong. If you are alone, tell someone what you are doing and when to check on you, and leave the door unlocked.

  • Start low, go slow

    Potency of illicit substances is unpredictable and varies between batches. Using a smaller amount first and waiting gives you information about strength before you take more.

  • Avoid mixing

    Combining substances — especially opioids, alcohol, benzodiazepines, gabapentinoids or other sedatives — greatly increases the risk of stopped breathing and death.

  • Tolerance drops fast

    After a break — prison, hospital, detox, treatment or simply a pause — the same amount you used before can be dangerous. Restart much lower.

  • Carry naloxone if opioids may be involved

    Naloxone temporarily reverses opioid overdose. It is free in the UK and can be supplied to people likely to witness an overdose. Always call 999 as well.

  • Look after the basics

    Hydration, food, sleep, wound care and dental care all affect how well your body copes. Blood-borne virus testing and vaccination are free and confidential.

Naloxone

Naloxone saves lives — and it's free

Naloxone temporarily reverses the effects of an opioid overdose, giving time for an ambulance to arrive. In the UK it can be supplied without a prescription to people likely to need it, including family members, friends and peers.

  • Ask a drug and alcohol service, needle and syringe programme, or participating pharmacy about a free kit and training.
  • Naloxone only works on opioids — but it is safe to give if you are unsure and opioids may be involved.
  • It wears off before many opioids do, so the person can deteriorate again. Always call 999.
  • Stay with the person, keep their airway clear, and follow the call handler's instructions.

Safer injecting

  • Use sterile, single-use injecting equipment every time — needle and syringe programmes are free and confidential.
  • Never share needles, syringes, filters, spoons, water or swabs; hepatitis C can be passed on through shared equipment.
  • Wash your hands, use a clean surface and rotate injection sites where possible.
  • Dispose of used equipment in a sharps bin — services provide these free.
  • Get free, confidential testing for hepatitis B, hepatitis C and HIV. Hepatitis C treatment is available and highly effective.
  • Seek medical help promptly for redness, swelling, heat, pain or an abscess — infections can become serious quickly.

Alcohol and sedatives

Two situations where stopping suddenly can be dangerous

With alcohol and with benzodiazepines, abrupt withdrawal after heavy, regular use can cause seizures and other serious medical problems.

Alcohol

If you drink heavily every day, do not stop abruptly without medical advice. Speak to a GP, pharmacist or alcohol service about a safe plan — medically supported withdrawal is available and is often provided in the community.

Benzodiazepines and similar

Reductions should be planned and gradual with a prescriber. Illicit "benzos" are often stronger or different from what they are sold as, and are frequently involved in UK drug deaths when combined with opioids.

Find help near me